Acetyl-CoA Carboxylase alpha anticorps (pSer79)

N° du produit ABIN3020067

L’anticorps Lapin Polyclonal anti-Acetyl-CoA Carboxylase alpha a été validé pour WB. Il convient pour détecter Acetyl-CoA Carboxylase alpha dans des échantillons de Humain. Il y a 1 publication disponible.

Aperçu rapide pour Acetyl-CoA Carboxylase alpha anticorps (pSer79) (ABIN3020067)

Antigène: Acetyl-CoA Carboxylase alpha (ACACA)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Acetyl-CoA Carboxylase alpha est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Acetyl-CoA Carboxylase alpha anticorps

Épitope: pSer79

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Phosphorylated Antibodies

Purification: Affinity purification

Immunogène: A phospho specific peptide corresponding to residues surrounding S79 of human ACC1

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-Acetyl-CoA Carboxylase alpha (ABIN3020067)

Li, Zhao, Chen, Fu, Shi, Liu, Liu, Xiong, Liu, Yang, Xiao: "Depsidone and xanthones from Garcinia xanthochymus with hypoglycemic activity and the mechanism of promoting glucose uptake in L6 myotubes." dans: Bioorganic & medicinal chemistry, Vol. 25, Issue 24, pp. 6605-6613, (2017) (PubMed).

Détails sur Acetyl-CoA Carboxylase alpha

Antigène: Acetyl-CoA Carboxylase alpha (ACACA)

Autre désignation: ACC1

Sujet: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.,ACACA,ACAC,ACACAD,ACC,ACC1,ACCA,Endocrine & Metabolism,Lipid Metabolism,AMPK Signaling Pathway,Warburg Effect,Protein phosphorylation,ACC1

Poids moléculaire: 257 kDa/259 kDa/265 kDa/269 kDa

ID gène: 31

UniProt: Q13085

Pathways: AMPK Signaling, Ribonucleoside Biosynthetic Process, L'effet Warburg